Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2c. Descriptive Summary for Subjects Aged 30-39 Years



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

33

11.6

5.4

0.9

10.9

8.1, 13.5

4.6, 29.1


IgD+ Memory B cells

33

7.5

5.3

0.9

5.7

4.4, 9.8

1.3, 28.0


IgD- Memory B cells

33

18.9

9.2

1.6

16.7

11.7, 25.5

5.2, 38.9


IgD-CD27- B cells

33

9.6

5.0

0.9

8.9

6.5, 11.7

1.4, 23.4


Naïve B cells

33

63.9

13.7

2.4

67.5

54.7, 73.6

26.8, 84.3


Plasma cells

33

1.2

1.2

0.2

0.8

0.4, 1.5

0.1, 5.0


Plasmablasts

33

0.5

0.5

0.1

0.3

0.1, 0.4

0.0, 2.3


Transitional B cells

33

4.1

2.3

0.4

3.8

2.3, 5.4

0.9, 10.6

DCMNK

CD11c+CD123+ DC (DC)

33

6.6

8.5

1.5

2.7

1.1, 8.5

0.1, 37.9


CD11c+CD123+ DC (Live Scatter)

33

0.1

0.2

0.0

0.0

0.0, 0.1

0.0, 0.8


CD14+ Monocytes

33

77.3

9.5

1.7

78.4

73.1, 85.6

57.5, 90.2


CD16+CD14- Monocytes

33

9.3

7.1

1.2

7.2

4.3, 10.6

0.3, 29.5


CD16+CD56+ NK cells

33

74.4

12.2

2.1

76.7

68.6, 83.7

35.8, 90.8


CD16+CD56- NK cells

33

9.8

7.4

1.3

9.0

4.7, 11.4

2.3, 35.0


CD16-CD56+ NK cells

33

14.9

10.1

1.8

11.5

8.8, 17.5

4.8, 59.5


Classical Monocytes

33

75.6

9.9

1.7

76.3

70.9, 84.1

53.7, 89.9


Dendritic cells (Lin-)

33

2.0

0.8

0.1

1.8

1.5, 2.3

0.8, 4.7


Dendritic cells (Live Scatter)

33

1.4

0.5

0.1

1.4

1.2, 1.6

0.6, 2.7


Monocytes

33

10.1

3.8

0.7

8.9

8.1, 12.2

2.8, 18.7


Myeloid DC (DC)

33

49.1

11.0

1.9

48.9

43.2, 56.5

23.9, 72.7


Myeloid DC (Live Scatter)

33

0.7

0.3

0.0

0.7

0.5, 0.9

0.3, 1.4


NK cells

33

9.0

4.9

0.8

7.4

5.9, 12.1

2.1, 24.3


Plasmacytoid DC (DC)

33

23.5

7.7

1.3

21.5

17.8, 27.4

13.7, 39.3


Plasmacytoid DC (Live Scatter)

33

0.3

0.2

0.0

0.3

0.2, 0.4

0.1, 1.0

Tcell

Activated CD4+ T cells

33

1.9

0.9

0.2

1.8

1.3, 2.3

0.4, 4.8


Activated CD8+ T cells

33

4.7

3.6

0.6

3.4

2.5, 6.5

0.9, 19.0


Activated Central Memory CD4+ T cells

33

1.6

0.6

0.1

1.6

1.1, 2.0

0.4, 2.8


Activated Central Memory CD8+ T cells

33

5.7

3.7

0.6

4.4

3.2, 7.5

1.7, 16.9


Activated Effector CD4+ T cells

33

3.8

2.8

0.5

3.1

1.6, 5.0

0.3, 10.3


Activated Effector CD8+ T cells

33

7.9

8.2

1.4

5.0

3.1, 9.9

1.1, 38.4


Activated Effector Memory CD4+ T cells

33

5.4

2.3

0.4

5.2

3.6, 6.4

1.5, 12.5


Activated Effector Memory CD8+ T cells

33

11.4

6.6

1.1

10.6

5.2, 16.8

3.1, 26.3


Activated Naive CD4+ T cells

33

1.4

1.0

0.2

1.5

0.5, 2.1

0.1, 5.2


Activated Naive CD8+ T cells

33

2.1

1.6

0.3

1.4

1.0, 2.8

0.3, 6.4


Average CD4+ T cells

33

50.4

7.1

1.2

50.6

45.6, 54.0

37.0, 66.3


Average Lymphocytes

33

64.8

8.1

1.4

65.8

60.1, 71.1

47.5, 75.7


Average T cells

33

76.9

7.0

1.2

78.3

70.5, 81.3

64.1, 88.4


CD8+ T cells

33

22.2

7.6

1.3

22.1

16.8, 24.5

9.0, 45.4


Central Memory CD4+ T cells

33

47.1

11.4

2.0

48.3

39.0, 53.3

21.8, 67.8


Central Memory CD8+ T cells

33

10.4

6.2

1.1

9.3

6.1, 14.3

2.0, 26.7


Effector CD4+ T cells

33

1.9

3.0

0.5

1.0

0.4, 1.7

0.1, 12.4


Effector CD8+ T cells

33

25.4

13.3

2.3

23.8

14.4, 35.3

7.2, 54.4


Effector Memory CD4+ T cells

33

11.8

7.5

1.3

10.9

8.7, 13.1

3.9, 47.3


Effector Memory CD8+ T cells

33

10.0

5.1

0.9

9.3

6.4, 14.3

2.3, 20.3


Naive CD4+ T cells

33

38.9

14.1

2.5

37.7

25.9, 49.7

11.8, 73.6


Naive CD8+ T cells

33

54.2

15.5

2.7

57.9

40.5, 64.3

25.7, 83.0

Tfh

Activated T follicular helper

33

0.5

0.2

0.0

0.5

0.3, 0.6

0.1, 1.3


Medium Activated T follicular helper

33

17.6

4.4

0.8

16.5

14.3, 19.9

10.6, 27.4


T follicular helper

33

13.0

3.6

0.6

12.8

10.9, 14.6

7.3, 24.1


T follicular helper type 1

33

27.1

6.7

1.2

27.2

22.1, 32.1

14.3, 42.1


T follicular helper type 17

33

32.7

6.9

1.2

32.3

27.7, 36.8

21.1, 50.1


T follicular helper type 2

33

24.0

4.4

0.8

23.8

20.8, 26.6

15.0, 33.0


T follicular regulatory

33

5.1

2.3

0.4

4.7

3.6, 6.0

2.3, 12.2

Treg

Activated Memory Treg cells

33

48.4

6.0

1.0

48.3

44.0, 53.7

38.2, 61.1


Activated Naïve Treg cells

33

2.2

1.8

0.3

1.6

0.8, 3.0

0.4, 7.6


Effector Treg cells

33

63.3

8.8

1.5

63.2

59.2, 67.2

43.3, 84.5


HLA-DR- Memory Treg cells

33

41.6

6.5

1.1

41.1

39.3, 46.5

24.6, 53.6


HLA-DR- Naive Treg cells

33

7.8

2.7

0.5

7.4

5.4, 8.9

4.2, 14.9


Treg cells

33

6.9

1.6

0.3

6.9

6.1, 7.6

4.1, 11.6

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile