|
|
Table 2a. Descriptive Summary for Overall Study Population |
Panel |
Cell Subset |
N |
Mean |
SD |
SE |
Median |
Q1, Q3 |
Min, Max |
Bcell |
B cells |
127 |
11.0 |
4.6 |
0.4 |
10.2 |
7.8, 13.5 |
1.8, 29.1 |
|
IgD+ Memory B cells |
127 |
7.4 |
4.5 |
0.4 |
6.4 |
4.3, 9.8 |
1.3, 28.0 |
|
IgD- Memory B cells |
127 |
20.5 |
9.1 |
0.8 |
19.3 |
13.4, 25.7 |
4.2, 50.9 |
|
IgD-CD27- B cells |
127 |
10.1 |
5.7 |
0.5 |
8.8 |
5.9, 12.8 |
1.4, 28.9 |
|
Naïve B cells |
127 |
62.0 |
13.2 |
1.2 |
64.9 |
53.9, 70.6 |
20.9, 86.6 |
|
Plasma cells |
127 |
1.2 |
0.9 |
0.1 |
0.8 |
0.5, 1.6 |
0.1, 5.0 |
|
Plasmablasts |
127 |
0.4 |
0.4 |
0.0 |
0.3 |
0.2, 0.6 |
0.0, 2.3 |
|
Transitional B cells |
127 |
4.2 |
3.2 |
0.3 |
3.6 |
2.1, 5.6 |
0.4, 21.1 |
DCMNK |
CD11c+CD123+ DC (DC) |
127 |
6.8 |
9.2 |
0.8 |
3.0 |
1.0, 8.9 |
0.1, 52.4 |
|
CD11c+CD123+ DC (Live Scatter) |
127 |
0.1 |
0.2 |
0.0 |
0.0 |
0.0, 0.1 |
0.0, 0.8 |
|
CD14+ Monocytes |
127 |
79.6 |
8.1 |
0.7 |
80.8 |
75.9, 85.8 |
53.7, 93.1 |
|
CD16+CD14- Monocytes |
127 |
8.9 |
6.0 |
0.5 |
7.5 |
4.4, 12.3 |
0.3, 30.2 |
|
CD16+CD56+ NK cells |
127 |
75.8 |
12.1 |
1.1 |
79.1 |
68.8, 84.9 |
25.4, 91.1 |
|
CD16+CD56- NK cells |
127 |
10.0 |
7.7 |
0.7 |
8.0 |
4.8, 12.5 |
1.8, 39.5 |
|
CD16-CD56+ NK cells |
127 |
13.3 |
9.3 |
0.8 |
11.0 |
7.4, 16.5 |
3.7, 65.7 |
|
Classical Monocytes |
127 |
77.3 |
8.6 |
0.8 |
78.0 |
73.4, 84.0 |
51.3, 92.3 |
|
Dendritic cells (Lin-) |
127 |
1.9 |
0.8 |
0.1 |
1.7 |
1.3, 2.3 |
0.4, 4.7 |
|
Dendritic cells (Live Scatter) |
127 |
1.4 |
0.5 |
0.0 |
1.3 |
1.0, 1.7 |
0.3, 2.7 |
|
Monocytes |
127 |
10.5 |
4.1 |
0.4 |
10.2 |
7.5, 14.2 |
2.4, 23.2 |
|
Myeloid DC (DC) |
127 |
46.5 |
11.9 |
1.1 |
46.7 |
37.4, 54.3 |
18.8, 75.7 |
|
Myeloid DC (Live Scatter) |
127 |
0.6 |
0.3 |
0.0 |
0.6 |
0.4, 0.8 |
0.1, 1.8 |
|
NK cells |
127 |
8.7 |
4.7 |
0.4 |
7.8 |
5.1, 11.4 |
2.1, 24.3 |
|
Plasmacytoid DC (DC) |
127 |
25.4 |
10.1 |
0.9 |
23.9 |
17.5, 32.7 |
3.9, 55.1 |
|
Plasmacytoid DC (Live Scatter) |
127 |
0.3 |
0.2 |
0.0 |
0.3 |
0.2, 0.4 |
0.1, 1.0 |
Tcell |
Activated CD4+ T cells |
123 |
1.8 |
0.9 |
0.1 |
1.6 |
1.2, 2.1 |
0.4, 5.8 |
|
Activated CD8+ T cells |
123 |
4.9 |
3.5 |
0.3 |
3.8 |
2.5, 6.3 |
0.6, 19.0 |
|
Activated Central Memory CD4+ T cells |
123 |
1.6 |
0.7 |
0.1 |
1.5 |
1.1, 2.0 |
0.4, 3.7 |
|
Activated Central Memory CD8+ T cells |
122 |
5.9 |
3.9 |
0.4 |
4.6 |
3.1, 7.5 |
1.2, 21.4 |
|
Activated Effector CD4+ T cells |
123 |
3.7 |
2.9 |
0.3 |
2.8 |
1.6, 5.5 |
0.3, 15.0 |
|
Activated Effector CD8+ T cells |
122 |
7.5 |
6.5 |
0.6 |
5.1 |
3.5, 9.9 |
1.0, 38.4 |
|
Activated Effector Memory CD4+ T cells |
123 |
5.8 |
2.8 |
0.3 |
5.3 |
3.8, 6.8 |
1.5, 21.8 |
|
Activated Effector Memory CD8+ T cells |
122 |
12.2 |
7.9 |
0.7 |
10.5 |
6.8, 15.3 |
1.4, 54.8 |
|
Activated Naive CD4+ T cells |
123 |
1.0 |
0.9 |
0.1 |
0.8 |
0.4, 1.4 |
0.1, 5.2 |
|
Activated Naive CD8+ T cells |
122 |
2.0 |
1.6 |
0.1 |
1.4 |
0.8, 2.8 |
0.2, 7.9 |
|
Average CD4+ T cells |
127 |
52.1 |
8.3 |
0.7 |
52.1 |
45.8, 57.8 |
32.6, 72.8 |
|
Average Lymphocytes |
127 |
64.0 |
9.7 |
0.9 |
65.9 |
59.6, 70.9 |
34.5, 85.5 |
|
Average T cells |
127 |
77.8 |
6.3 |
0.6 |
78.0 |
73.3, 82.7 |
64.1, 93.0 |
|
CD8+ T cells |
123 |
21.1 |
6.9 |
0.6 |
20.7 |
16.5, 24.2 |
5.9, 45.4 |
|
Central Memory CD4+ T cells |
123 |
45.6 |
11.4 |
1.0 |
46.6 |
37.7, 53.3 |
21.8, 77.6 |
|
Central Memory CD8+ T cells |
122 |
10.7 |
6.5 |
0.6 |
9.4 |
5.7, 14.0 |
1.7, 32.8 |
|
Effector CD4+ T cells |
123 |
2.8 |
4.1 |
0.4 |
1.2 |
0.6, 3.2 |
0.0, 25.5 |
|
Effector CD8+ T cells |
122 |
29.5 |
14.9 |
1.3 |
26.1 |
17.4, 39.9 |
1.7, 73.0 |
|
Effector Memory CD4+ T cells |
123 |
10.9 |
6.0 |
0.5 |
9.8 |
6.6, 13.4 |
2.3, 47.3 |
|
Effector Memory CD8+ T cells |
122 |
10.4 |
5.7 |
0.5 |
9.8 |
5.9, 15.1 |
2.3, 33.6 |
|
Naive CD4+ T cells |
123 |
40.4 |
14.4 |
1.3 |
39.5 |
27.1, 51.9 |
6.0, 73.6 |
|
Naive CD8+ T cells |
122 |
49.4 |
17.3 |
1.6 |
49.8 |
34.3, 64.3 |
16.4, 83.0 |
Tfh |
Activated T follicular helper |
127 |
0.5 |
0.2 |
0.0 |
0.4 |
0.3, 0.6 |
0.1, 1.3 |
|
Medium Activated T follicular helper |
127 |
17.6 |
4.4 |
0.4 |
16.8 |
14.4, 20.9 |
8.1, 27.8 |
|
T follicular helper |
127 |
12.9 |
3.8 |
0.3 |
12.8 |
10.0, 14.6 |
5.6, 24.3 |
|
T follicular helper type 1 |
127 |
25.9 |
6.2 |
0.6 |
25.8 |
22.1, 29.5 |
7.4, 42.1 |
|
T follicular helper type 17 |
127 |
33.8 |
7.2 |
0.6 |
33.8 |
28.4, 38.3 |
18.3, 59.1 |
|
T follicular helper type 2 |
127 |
24.5 |
5.5 |
0.5 |
23.9 |
20.8, 28.4 |
10.6, 40.0 |
|
T follicular regulatory |
127 |
4.7 |
2.1 |
0.2 |
4.4 |
3.1, 5.6 |
1.2, 13.6 |
Treg |
Activated Memory Treg cells |
127 |
46.1 |
8.6 |
0.8 |
45.9 |
40.1, 51.3 |
24.7, 70.1 |
|
Activated Naïve Treg cells |
127 |
2.3 |
2.6 |
0.2 |
1.4 |
0.7, 2.9 |
0.1, 17.0 |
|
Effector Treg cells |
127 |
64.6 |
13.7 |
1.2 |
65.0 |
56.9, 74.7 |
28.6, 92.1 |
|
HLA-DR- Memory Treg cells |
127 |
42.8 |
8.6 |
0.8 |
42.2 |
37.6, 48.8 |
21.1, 67.0 |
|
HLA-DR- Naive Treg cells |
127 |
8.9 |
4.7 |
0.4 |
7.8 |
5.3, 11.3 |
1.2, 32.8 |
|
Treg cells |
127 |
7.3 |
1.8 |
0.2 |
7.1 |
6.2, 8.4 |
3.2, 14.4 |
Two DCMNK gates are not reported because their values are ANR. |
|
|
|
N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile |