Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2q. Descriptive Summary for Non-Caucasian Subjects



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

76

12.2

4.7

0.5

11.5

9.0, 14.4

5.1, 29.1


IgD+ Memory B cells

76

6.3

4.2

0.5

5.3

3.7, 8.2

1.3, 28.0


IgD- Memory B cells

76

21.6

9.0

1.0

20.3

15.0, 26.6

7.0, 50.9


IgD-CD27- B cells

76

11.3

6.1

0.7

10.0

6.8, 13.7

3.4, 28.9


Naïve B cells

76

60.8

13.6

1.6

64.9

53.1, 69.8

20.9, 86.6


Plasma cells

76

1.3

1.0

0.1

0.9

0.5, 1.8

0.2, 5.0


Plasmablasts

76

0.5

0.4

0.0

0.4

0.2, 0.7

0.0, 2.3


Transitional B cells

76

4.3

3.6

0.4

3.2

2.0, 5.5

0.4, 21.1

DCMNK

CD11c+CD123+ DC (DC)

76

8.6

10.8

1.2

3.3

1.1, 10.5

0.3, 52.4


CD11c+CD123+ DC (Live Scatter)

76

0.1

0.2

0.0

0.0

0.0, 0.2

0.0, 0.8


CD14+ Monocytes

76

76.7

8.6

1.0

78.7

71.3, 82.8

53.7, 90.4


CD16+CD14- Monocytes

76

11.3

6.1

0.7

10.2

6.6, 14.8

0.5, 30.2


CD16+CD56+ NK cells

76

74.7

12.6

1.4

76.5

68.3, 84.3

25.4, 91.1


CD16+CD56- NK cells

76

11.8

8.4

1.0

9.3

5.9, 14.5

2.4, 39.5


CD16-CD56+ NK cells

76

12.6

9.0

1.0

10.6

7.4, 14.7

3.7, 65.7


Classical Monocytes

76

74.0

8.9

1.0

75.7

67.8, 80.1

51.3, 88.0


Dendritic cells (Lin-)

76

1.9

0.8

0.1

1.8

1.4, 2.3

0.4, 4.7


Dendritic cells (Live Scatter)

76

1.4

0.5

0.1

1.4

1.0, 1.7

0.3, 2.7


Monocytes

76

10.0

4.5

0.5

9.8

6.6, 13.3

2.4, 23.2


Myeloid DC (DC)

76

45.0

11.8

1.4

44.0

35.6, 52.7

18.8, 71.9


Myeloid DC (Live Scatter)

76

0.6

0.3

0.0

0.6

0.4, 0.8

0.1, 1.8


NK cells

76

9.0

4.6

0.5

8.2

5.3, 11.9

2.2, 21.9


Plasmacytoid DC (DC)

76

24.3

10.1

1.2

22.7

16.7, 31.4

3.9, 55.1


Plasmacytoid DC (Live Scatter)

76

0.3

0.2

0.0

0.3

0.2, 0.4

0.1, 1.0

Tcell

Activated CD4+ T cells

73

1.9

1.0

0.1

1.8

1.2, 2.2

0.4, 5.8


Activated CD8+ T cells

73

4.6

3.1

0.4

3.8

2.6, 5.6

0.6, 19.0


Activated Central Memory CD4+ T cells

73

1.6

0.7

0.1

1.4

1.0, 2.0

0.4, 3.7


Activated Central Memory CD8+ T cells

73

5.6

3.3

0.4

4.4

3.2, 7.1

1.2, 16.9


Activated Effector CD4+ T cells

73

3.3

2.8

0.3

2.4

1.5, 4.5

0.3, 14.8


Activated Effector CD8+ T cells

73

6.5

4.9

0.6

5.0

3.5, 7.9

1.0, 30.2


Activated Effector Memory CD4+ T cells

73

5.7

2.9

0.3

5.3

3.8, 6.7

1.5, 21.8


Activated Effector Memory CD8+ T cells

73

11.8

5.7

0.7

11.0

7.6, 14.7

1.4, 33.7


Activated Naive CD4+ T cells

73

1.2

1.0

0.1

0.9

0.4, 1.6

0.1, 5.2


Activated Naive CD8+ T cells

73

2.2

1.7

0.2

1.7

0.9, 2.8

0.2, 7.9


Average CD4+ T cells

76

50.6

8.4

1.0

50.4

45.0, 55.9

32.6, 72.8


Average Lymphocytes

76

64.2

10.3

1.2

66.4

59.8, 71.0

34.5, 85.5


Average T cells

76

76.7

6.0

0.7

76.4

72.2, 80.0

64.6, 88.6


CD8+ T cells

73

21.3

6.8

0.8

21.0

16.5, 24.5

9.0, 40.7


Central Memory CD4+ T cells

73

46.7

11.4

1.3

46.8

39.1, 54.7

22.3, 77.6


Central Memory CD8+ T cells

73

9.3

6.0

0.7

8.0

5.1, 12.1

1.7, 32.8


Effector CD4+ T cells

73

3.1

4.4

0.5

1.5

0.7, 3.4

0.2, 25.5


Effector CD8+ T cells

73

32.4

15.3

1.8

29.2

22.1, 44.1

7.2, 73.0


Effector Memory CD4+ T cells

73

12.0

6.4

0.8

10.9

8.3, 13.9

2.9, 47.3


Effector Memory CD8+ T cells

73

9.5

5.9

0.7

8.1

4.5, 13.9

2.3, 33.6


Naive CD4+ T cells

73

37.9

14.0

1.6

38.4

26.1, 48.1

6.0, 66.6


Naive CD8+ T cells

73

48.8

18.0

2.1

49.8

34.1, 64.3

17.4, 83.0

Tfh

Activated T follicular helper

76

0.5

0.2

0.0

0.4

0.3, 0.6

0.1, 1.1


Medium Activated T follicular helper

76

17.6

4.5

0.5

16.9

14.7, 21.0

8.1, 27.8


T follicular helper

76

13.9

3.8

0.4

13.6

11.8, 16.0

6.9, 24.3


T follicular helper type 1

76

22.9

4.9

0.6

23.0

20.3, 26.3

7.4, 32.5


T follicular helper type 17

76

36.9

6.7

0.8

36.7

32.1, 40.1

24.0, 59.1


T follicular helper type 2

76

23.8

5.7

0.7

23.4

19.6, 28.2

10.6, 39.9


T follicular regulatory

76

4.4

1.7

0.2

4.4

3.0, 5.3

1.2, 9.7

Treg

Activated Memory Treg cells

76

44.9

8.9

1.0

44.2

38.3, 51.2

24.7, 67.7


Activated Naïve Treg cells

76

2.6

2.9

0.3

1.9

0.8, 3.5

0.1, 17.0


Effector Treg cells

76

66.4

13.0

1.5

67.5

61.3, 74.5

34.3, 92.1


HLA-DR- Memory Treg cells

76

42.8

9.2

1.1

42.1

37.3, 49.0

21.1, 67.0


HLA-DR- Naive Treg cells

76

9.7

5.4

0.6

8.0

6.0, 11.8

1.2, 32.8


Treg cells

76

7.7

1.7

0.2

7.6

6.5, 8.9

4.4, 14.4

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile