Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2m. Descriptive Summary for Male Subjects Aged 30-39 Years



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

16

11.2

5.1

1.3

11.1

6.8, 15.6

4.6, 21.9


IgD+ Memory B cells

16

5.9

3.2

0.8

5.0

3.9, 6.7

2.2, 14.4


IgD- Memory B cells

16

16.9

6.9

1.7

16.4

11.9, 22.4

6.6, 28.9


IgD-CD27- B cells

16

9.3

3.3

0.8

9.2

7.3, 11.1

1.4, 17.4


Naïve B cells

16

67.8

9.1

2.3

68.8

60.6, 74.2

53.1, 82.3


Plasma cells

16

1.3

1.4

0.4

0.9

0.4, 1.5

0.1, 5.0


Plasmablasts

16

0.5

0.6

0.2

0.3

0.1, 0.5

0.0, 2.3


Transitional B cells

16

4.5

2.2

0.6

4.3

2.3, 6.2

1.6, 8.2

DCMNK

CD11c+CD123+ DC (DC)

16

7.7

10.3

2.6

4.6

1.1, 8.0

0.3, 37.9


CD11c+CD123+ DC (Live Scatter)

16

0.1

0.2

0.0

0.1

0.0, 0.2

0.0, 0.8


CD14+ Monocytes

16

76.8

11.7

2.9

82.5

63.7, 86.0

57.5, 89.0


CD16+CD14- Monocytes

16

10.1

9.2

2.3

6.0

3.7, 17.0

0.3, 29.5


CD16+CD56+ NK cells

16

73.9

13.4

3.4

77.2

68.9, 84.0

35.8, 90.8


CD16+CD56- NK cells

16

7.6

4.5

1.1

7.7

3.6, 10.7

2.3, 17.9


CD16-CD56+ NK cells

16

17.2

13.0

3.2

14.7

9.8, 21.4

5.4, 59.5


Classical Monocytes

16

74.9

12.2

3.0

79.4

61.2, 84.7

53.7, 87.7


Dendritic cells (Lin-)

16

2.0

0.7

0.2

2.0

1.5, 2.3

0.8, 4.0


Dendritic cells (Live Scatter)

16

1.5

0.5

0.1

1.4

1.1, 1.6

0.7, 2.6


Monocytes

16

9.7

4.5

1.1

8.1

7.0, 13.0

2.8, 18.7


Myeloid DC (DC)

16

47.6

9.9

2.5

51.1

39.4, 53.8

26.4, 60.4


Myeloid DC (Live Scatter)

16

0.7

0.3

0.1

0.7

0.5, 0.8

0.3, 1.2


NK cells

16

8.7

3.7

0.9

8.6

6.1, 10.9

2.1, 14.9


Plasmacytoid DC (DC)

16

24.1

8.1

2.0

21.9

17.8, 32.0

14.2, 37.3


Plasmacytoid DC (Live Scatter)

16

0.4

0.2

0.0

0.3

0.2, 0.4

0.2, 1.0

Tcell

Activated CD4+ T cells

16

1.8

0.8

0.2

1.7

1.2, 2.1

0.9, 3.9


Activated CD8+ T cells

16

4.1

1.9

0.5

3.3

2.7, 5.8

1.5, 7.2


Activated Central Memory CD4+ T cells

16

1.6

0.6

0.1

1.6

1.1, 1.9

0.9, 2.8


Activated Central Memory CD8+ T cells

16

6.5

4.4

1.1

5.7

3.3, 8.5

1.7, 16.9


Activated Effector CD4+ T cells

16

2.7

1.6

0.4

2.3

1.5, 3.7

1.1, 6.1


Activated Effector CD8+ T cells

16

5.7

4.1

1.0

4.1

3.7, 6.8

1.1, 16.1


Activated Effector Memory CD4+ T cells

16

4.7

1.8

0.4

4.5

3.4, 5.4

2.6, 10.0


Activated Effector Memory CD8+ T cells

16

10.5

5.4

1.3

10.1

5.9, 14.7

4.2, 21.3


Activated Naive CD4+ T cells

16

1.4

1.3

0.3

1.0

0.4, 2.1

0.3, 5.2


Activated Naive CD8+ T cells

16

2.2

1.7

0.4

1.6

1.1, 2.8

0.6, 6.4


Average CD4+ T cells

16

49.1

6.0

1.5

50.2

43.3, 53.5

40.6, 59.0


Average Lymphocytes

16

64.3

7.4

1.9

63.4

60.2, 70.4

47.5, 75.7


Average T cells

16

76.2

7.0

1.7

78.8

69.6, 81.0

64.6, 87.2


CD8+ T cells

16

22.3

9.6

2.4

19.7

16.3, 23.2

9.0, 45.4


Central Memory CD4+ T cells

16

44.9

12.9

3.2

48.6

34.1, 55.3

21.8, 63.3


Central Memory CD8+ T cells

16

10.8

7.8

1.9

9.5

4.7, 15.8

2.0, 26.7


Effector CD4+ T cells

16

2.4

3.9

1.0

1.1

0.4, 1.8

0.2, 12.4


Effector CD8+ T cells

16

25.7

14.5

3.6

24.2

12.9, 36.5

8.6, 54.4


Effector Memory CD4+ T cells

16

13.7

9.7

2.4

11.7

10.8, 14.5

3.9, 47.3


Effector Memory CD8+ T cells

16

10.3

5.2

1.3

9.2

6.3, 13.7

3.4, 20.3


Naive CD4+ T cells

16

38.7

16.7

4.2

36.9

25.2, 51.3

11.8, 73.6


Naive CD8+ T cells

16

53.2

17.5

4.4

55.2

40.3, 66.0

25.7, 83.0

Tfh

Activated T follicular helper

16

0.5

0.3

0.1

0.5

0.3, 0.6

0.2, 1.3


Medium Activated T follicular helper

16

17.8

4.0

1.0

17.4

14.2, 20.3

12.5, 25.6


T follicular helper

16

12.7

3.6

0.9

12.3

10.3, 14.7

7.3, 20.3


T follicular helper type 1

16

23.8

5.7

1.4

22.6

20.6, 28.7

14.3, 36.3


T follicular helper type 17

16

35.9

7.6

1.9

36.2

30.9, 40.0

21.1, 50.1


T follicular helper type 2

16

24.7

4.2

1.1

24.1

22.2, 26.4

17.0, 33.0


T follicular regulatory

16

5.0

2.0

0.5

4.7

3.6, 6.3

2.3, 8.9

Treg

Activated Memory Treg cells

16

47.5

5.4

1.4

47.0

44.1, 52.1

38.2, 56.5


Activated Naïve Treg cells

16

2.8

2.1

0.5

2.7

1.0, 4.0

0.4, 7.6


Effector Treg cells

16

63.3

10.1

2.5

64.5

55.9, 68.1

43.3, 81.7


HLA-DR- Memory Treg cells

16

40.8

5.9

1.5

40.6

38.1, 43.5

29.5, 51.4


HLA-DR- Naive Treg cells

16

8.9

3.1

0.8

8.3

6.6, 11.4

4.2, 14.9


Treg cells

16

7.1

1.6

0.4

7.0

6.5, 7.8

4.4, 11.6

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile