Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2k. Descriptive Summary for Male Subjects



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

65

10.6

3.7

0.5

10.2

7.8, 13.3

4.6, 21.9


IgD+ Memory B cells

65

7.0

4.0

0.5

5.7

4.3, 9.5

1.6, 17.8


IgD- Memory B cells

65

21.0

9.7

1.2

19.7

12.9, 26.3

4.2, 50.9


IgD-CD27- B cells

65

11.4

6.0

0.7

10.3

7.3, 14.3

1.4, 28.9


Naïve B cells

65

60.6

13.9

1.7

62.1

53.1, 70.1

20.9, 85.7


Plasma cells

65

1.3

1.0

0.1

0.9

0.5, 1.8

0.1, 5.0


Plasmablasts

65

0.5

0.4

0.1

0.4

0.2, 0.6

0.0, 2.3


Transitional B cells

65

3.4

2.3

0.3

2.7

1.7, 4.6

0.4, 10.5

DCMNK

CD11c+CD123+ DC (DC)

65

6.8

10.1

1.3

3.0

1.0, 6.9

0.2, 52.4


CD11c+CD123+ DC (Live Scatter)

65

0.1

0.2

0.0

0.0

0.0, 0.1

0.0, 0.8


CD14+ Monocytes

65

79.5

8.8

1.1

81.0

75.5, 86.2

53.7, 92.6


CD16+CD14- Monocytes

65

8.7

6.6

0.8

7.4

4.3, 11.2

0.3, 30.2


CD16+CD56+ NK cells

65

74.8

12.7

1.6

79.2

68.1, 84.4

35.8, 90.8


CD16+CD56- NK cells

65

10.0

8.1

1.0

8.2

4.3, 12.5

1.8, 39.5


CD16-CD56+ NK cells

65

14.2

9.7

1.2

11.1

7.9, 17.8

4.5, 59.5


Classical Monocytes

65

77.4

9.3

1.2

79.4

73.7, 84.4

51.7, 92.0


Dendritic cells (Lin-)

65

2.1

0.8

0.1

2.0

1.6, 2.5

0.7, 4.4


Dendritic cells (Live Scatter)

65

1.5

0.5

0.1

1.4

1.2, 1.8

0.6, 2.6


Monocytes

65

10.1

4.5

0.6

9.9

6.7, 13.1

2.8, 23.2


Myeloid DC (DC)

65

48.0

12.0

1.5

48.1

38.7, 56.7

19.7, 75.7


Myeloid DC (Live Scatter)

65

0.7

0.3

0.0

0.7

0.5, 0.8

0.1, 1.8


NK cells

65

8.4

4.0

0.5

8.1

5.2, 10.6

2.1, 19.8


Plasmacytoid DC (DC)

65

24.8

10.1

1.3

23.1

17.5, 31.3

3.9, 55.1


Plasmacytoid DC (Live Scatter)

65

0.4

0.2

0.0

0.3

0.2, 0.5

0.1, 1.0

Tcell

Activated CD4+ T cells

64

1.8

0.8

0.1

1.7

1.2, 2.1

0.7, 4.6


Activated CD8+ T cells

64

4.5

3.1

0.4

3.4

2.5, 5.6

0.6, 15.8


Activated Central Memory CD4+ T cells

64

1.7

0.7

0.1

1.6

1.2, 2.0

0.6, 3.7


Activated Central Memory CD8+ T cells

64

5.8

3.8

0.5

4.7

3.1, 7.1

1.4, 17.8


Activated Effector CD4+ T cells

64

3.6

3.1

0.4

2.5

1.5, 4.9

0.5, 15.0


Activated Effector CD8+ T cells

64

6.0

4.5

0.6

4.5

3.5, 6.6

1.0, 21.4


Activated Effector Memory CD4+ T cells

64

5.7

2.5

0.3

5.1

4.1, 6.8

2.1, 14.0


Activated Effector Memory CD8+ T cells

64

10.8

5.9

0.7

9.4

6.6, 13.6

3.6, 33.7


Activated Naive CD4+ T cells

64

1.1

1.0

0.1

0.8

0.4, 1.4

0.1, 5.2


Activated Naive CD8+ T cells

64

2.2

1.7

0.2

1.6

1.0, 2.9

0.2, 7.9


Average CD4+ T cells

65

51.8

8.8

1.1

51.9

45.6, 57.2

34.2, 72.8


Average Lymphocytes

65

62.4

11.0

1.4

65.1

53.8, 70.8

34.5, 85.5


Average T cells

65

77.5

5.9

0.7

77.9

73.9, 82.2

64.6, 87.2


CD8+ T cells

64

21.0

8.0

1.0

20.1

16.0, 24.4

5.9, 45.4


Central Memory CD4+ T cells

64

46.6

11.7

1.5

48.7

37.0, 55.3

21.8, 69.6


Central Memory CD8+ T cells

64

11.4

7.5

0.9

9.8

5.2, 15.5

1.7, 32.8


Effector CD4+ T cells

64

3.0

4.8

0.6

1.4

0.4, 2.4

0.0, 25.5


Effector CD8+ T cells

64

30.2

16.3

2.0

25.5

16.5, 41.6

1.7, 73.0


Effector Memory CD4+ T cells

64

10.9

6.7

0.8

10.8

6.0, 13.7

2.3, 47.3


Effector Memory CD8+ T cells

64

10.1

5.2

0.7

9.6

5.4, 14.8

2.5, 20.7


Naive CD4+ T cells

64

39.2

15.1

1.9

38.0

26.1, 51.0

11.8, 73.6


Naive CD8+ T cells

64

48.3

18.9

2.4

47.6

31.6, 66.6

16.4, 83.0

Tfh

Activated T follicular helper

65

0.5

0.3

0.0

0.4

0.2, 0.6

0.1, 1.3


Medium Activated T follicular helper

65

17.4

4.5

0.6

16.8

14.0, 20.8

8.1, 26.6


T follicular helper

65

13.3

3.7

0.5

13.1

11.1, 15.1

5.6, 20.6


T follicular helper type 1

65

24.1

5.8

0.7

24.2

21.0, 28.4

7.4, 37.7


T follicular helper type 17

65

35.2

7.6

0.9

34.4

29.8, 39.1

21.1, 59.1


T follicular helper type 2

65

25.1

5.6

0.7

24.5

21.8, 29.8

10.6, 39.9


T follicular regulatory

65

4.8

2.1

0.3

4.3

3.1, 5.7

2.0, 13.6

Treg

Activated Memory Treg cells

65

46.3

9.1

1.1

45.2

40.5, 51.9

29.0, 70.1


Activated Naïve Treg cells

65

3.1

3.1

0.4

2.4

1.3, 3.7

0.4, 17.0


Effector Treg cells

65

63.7

13.9

1.7

66.1

52.6, 71.9

28.6, 92.1


HLA-DR- Memory Treg cells

65

40.4

8.1

1.0

40.1

35.4, 46.2

21.1, 57.8


HLA-DR- Naive Treg cells

65

10.2

5.3

0.7

10.1

5.9, 12.3

1.2, 32.8


Treg cells

65

7.8

1.9

0.2

7.6

6.5, 8.8

4.4, 14.4

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile