Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2u. Descriptive Summary for Male, Non-Caucasian Subjects



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

41

11.4

3.3

0.5

11.5

8.9, 14.1

5.1, 16.8


IgD+ Memory B cells

41

6.4

3.7

0.6

5.1

4.0, 9.3

1.6, 16.2


IgD- Memory B cells

41

23.1

9.9

1.5

22.6

16.1, 27.2

7.0, 50.9


IgD-CD27- B cells

41

13.2

6.0

0.9

11.7

8.4, 16.3

4.3, 28.9


Naïve B cells

41

57.3

14.5

2.3

61.0

45.9, 67.4

20.9, 80.9


Plasma cells

41

1.4

1.1

0.2

1.2

0.6, 1.8

0.2, 5.0


Plasmablasts

41

0.5

0.4

0.1

0.4

0.2, 0.6

0.0, 2.3


Transitional B cells

41

3.2

2.4

0.4

2.4

1.6, 4.0

0.4, 10.5

DCMNK

CD11c+CD123+ DC (DC)

41

9.1

11.9

1.9

3.4

1.2, 9.7

0.3, 52.4


CD11c+CD123+ DC (Live Scatter)

41

0.1

0.2

0.0

0.1

0.0, 0.2

0.0, 0.8


CD14+ Monocytes

41

76.0

9.0

1.4

78.6

70.0, 81.2

53.7, 88.2


CD16+CD14- Monocytes

41

11.3

6.8

1.1

9.6

6.6, 13.9

2.2, 30.2


CD16+CD56+ NK cells

41

72.9

12.2

1.9

74.6

66.2, 84.2

45.0, 90.8


CD16+CD56- NK cells

41

12.5

9.0

1.4

11.1

6.2, 15.3

2.4, 39.5


CD16-CD56+ NK cells

41

13.4

7.8

1.2

11.0

7.8, 17.8

4.5, 33.7


Classical Monocytes

41

73.7

9.5

1.5

76.1

65.8, 79.6

51.7, 87.1


Dendritic cells (Lin-)

41

2.1

0.8

0.1

2.0

1.6, 2.3

0.8, 4.2


Dendritic cells (Live Scatter)

41

1.5

0.5

0.1

1.4

1.2, 1.8

0.7, 2.6


Monocytes

41

9.2

4.7

0.7

8.3

5.3, 11.0

2.8, 23.2


Myeloid DC (DC)

41

46.6

11.7

1.8

44.6

38.0, 55.2

22.6, 71.9


Myeloid DC (Live Scatter)

41

0.7

0.3

0.1

0.6

0.5, 0.8

0.2, 1.8


NK cells

41

8.7

4.0

0.6

8.2

5.6, 11.4

2.2, 19.8


Plasmacytoid DC (DC)

41

23.9

10.4

1.6

20.9

16.8, 31.2

3.9, 55.1


Plasmacytoid DC (Live Scatter)

41

0.4

0.2

0.0

0.3

0.2, 0.5

0.1, 1.0

Tcell

Activated CD4+ T cells

41

1.9

0.8

0.1

1.8

1.4, 2.1

0.7, 4.6


Activated CD8+ T cells

41

4.5

2.7

0.4

3.9

2.6, 5.3

0.6, 12.3


Activated Central Memory CD4+ T cells

41

1.7

0.7

0.1

1.6

1.2, 1.9

0.7, 3.4


Activated Central Memory CD8+ T cells

41

5.9

3.6

0.6

4.8

3.4, 6.5

1.8, 16.9


Activated Effector CD4+ T cells

41

3.2

2.7

0.4

2.1

1.4, 3.8

0.5, 14.8


Activated Effector CD8+ T cells

41

5.8

3.8

0.6

4.9

3.6, 6.5

1.0, 16.1


Activated Effector Memory CD4+ T cells

41

5.5

2.1

0.3

5.2

4.1, 6.7

2.6, 10.7


Activated Effector Memory CD8+ T cells

41

11.0

4.6

0.7

10.7

7.1, 13.8

3.6, 21.3


Activated Naive CD4+ T cells

41

1.3

1.1

0.2

1.1

0.6, 1.5

0.2, 5.2


Activated Naive CD8+ T cells

41

2.4

1.7

0.3

1.8

1.2, 2.8

0.2, 7.9


Average CD4+ T cells

41

50.3

8.8

1.4

50.3

44.0, 54.7

34.2, 72.8


Average Lymphocytes

41

62.1

11.7

1.8

65.8

53.8, 70.8

34.5, 85.5


Average T cells

41

76.5

5.9

0.9

76.2

72.5, 79.5

64.6, 86.8


CD8+ T cells

41

21.3

7.5

1.2

20.7

16.2, 24.5

9.0, 40.7


Central Memory CD4+ T cells

41

48.5

11.4

1.8

49.3

39.1, 56.7

27.3, 69.6


Central Memory CD8+ T cells

41

10.3

7.1

1.1

9.2

5.1, 12.8

1.7, 32.8


Effector CD4+ T cells

41

3.2

5.1

0.8

1.5

0.7, 2.6

0.2, 25.5


Effector CD8+ T cells

41

33.3

16.3

2.5

30.2

22.7, 46.1

8.6, 73.0


Effector Memory CD4+ T cells

41

12.2

7.4

1.2

10.9

7.9, 13.9

4.0, 47.3


Effector Memory CD8+ T cells

41

9.6

5.1

0.8

8.2

5.4, 14.4

2.5, 19.3


Naive CD4+ T cells

41

35.8

13.7

2.1

33.7

25.9, 47.4

11.8, 65.3


Naive CD8+ T cells

41

46.8

18.9

2.9

44.5

30.8, 66.3

17.4, 83.0

Tfh

Activated T follicular helper

41

0.5

0.3

0.0

0.4

0.2, 0.7

0.1, 1.1


Medium Activated T follicular helper

41

17.4

4.7

0.7

16.5

13.8, 21.9

8.1, 26.6


T follicular helper

41

14.4

3.3

0.5

13.8

12.2, 16.8

7.0, 20.6


T follicular helper type 1

41

21.7

5.0

0.8

22.5

19.7, 25.6

7.4, 30.0


T follicular helper type 17

41

38.1

7.6

1.2

37.4

31.8, 41.9

25.8, 59.1


T follicular helper type 2

41

24.3

6.1

1.0

23.4

19.9, 29.3

10.6, 39.9


T follicular regulatory

41

4.3

1.7

0.3

4.2

2.8, 5.1

2.0, 8.5

Treg

Activated Memory Treg cells

41

45.6

8.8

1.4

45.2

39.7, 51.0

29.0, 67.7


Activated Naïve Treg cells

41

3.7

3.3

0.5

3.0

2.0, 4.1

0.5, 17.0


Effector Treg cells

41

64.8

12.8

2.0

66.9

60.7, 68.5

36.6, 92.1


HLA-DR- Memory Treg cells

41

39.6

7.6

1.2

39.6

35.4, 43.8

21.1, 57.8


HLA-DR- Naive Treg cells

41

11.2

5.9

0.9

10.8

6.9, 13.1

1.2, 32.8


Treg cells

41

8.0

1.9

0.3

7.9

6.8, 9.1

4.4, 14.4

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile