Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2j. Descriptive Summary for Female Subjects Aged 50-66 Years



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

15

11.5

4.9

1.3

10.9

7.8, 14.3

4.0, 24.8


IgD+ Memory B cells

15

8.3

4.0

1.0

7.1

5.1, 11.2

2.9, 15.9


IgD- Memory B cells

15

20.0

8.4

2.2

19.3

13.5, 25.4

8.3, 35.5


IgD-CD27- B cells

15

6.8

3.6

0.9

6.3

3.6, 10.1

2.2, 14.8


Naïve B cells

15

64.9

9.9

2.6

66.6

58.8, 70.7

41.6, 79.7


Plasma cells

15

0.8

0.6

0.1

0.6

0.4, 1.0

0.1, 2.4


Plasmablasts

15

0.3

0.3

0.1

0.2

0.2, 0.4

0.1, 1.1


Transitional B cells

15

5.3

3.0

0.8

5.1

2.1, 7.9

1.2, 11.9

DCMNK

CD11c+CD123+ DC (DC)

15

8.5

7.8

2.0

3.3

1.1, 16.3

0.6, 21.2


CD11c+CD123+ DC (Live Scatter)

15

0.1

0.1

0.0

0.0

0.0, 0.2

0.0, 0.3


CD14+ Monocytes

15

81.2

7.4

1.9

81.4

77.3, 86.0

63.6, 93.1


CD16+CD14- Monocytes

15

9.8

4.5

1.2

9.7

6.3, 13.7

2.1, 17.8


CD16+CD56+ NK cells

15

81.0

7.2

1.9

81.6

72.9, 88.4

69.9, 91.1


CD16+CD56- NK cells

15

8.7

4.8

1.2

8.9

5.0, 11.9

2.5, 19.0


CD16-CD56+ NK cells

15

9.6

4.4

1.1

8.2

5.8, 12.6

5.3, 19.6


Classical Monocytes

15

78.3

7.5

1.9

78.0

75.5, 82.6

62.5, 92.3


Dendritic cells (Lin-)

15

1.4

0.5

0.1

1.2

1.1, 1.6

0.6, 2.3


Dendritic cells (Live Scatter)

15

0.9

0.4

0.1

0.9

0.8, 1.1

0.4, 1.8


Monocytes

15

12.0

3.2

0.8

13.2

10.1, 14.3

6.1, 16.0


Myeloid DC (DC)

15

43.4

12.7

3.3

43.7

33.9, 47.9

20.7, 68.3


Myeloid DC (Live Scatter)

15

0.4

0.2

0.0

0.4

0.3, 0.5

0.1, 0.8


NK cells

15

9.6

5.0

1.3

8.8

5.8, 14.0

2.4, 18.1


Plasmacytoid DC (DC)

15

24.4

11.7

3.0

20.0

15.7, 29.2

9.9, 51.4


Plasmacytoid DC (Live Scatter)

15

0.2

0.1

0.0

0.2

0.1, 0.3

0.1, 0.4

Tcell

Activated CD4+ T cells

14

1.4

0.5

0.1

1.3

1.0, 1.8

0.8, 2.5


Activated CD8+ T cells

14

5.3

3.0

0.8

4.8

3.1, 6.6

2.3, 14.0


Activated Central Memory CD4+ T cells

14

1.1

0.4

0.1

1.0

0.9, 1.2

0.6, 2.3


Activated Central Memory CD8+ T cells

14

3.3

1.3

0.3

3.0

2.7, 4.1

1.2, 5.5


Activated Effector CD4+ T cells

14

3.2

2.7

0.7

2.2

1.1, 4.5

0.4, 9.9


Activated Effector CD8+ T cells

14

8.0

5.0

1.3

6.9

5.4, 11.2

2.5, 21.9


Activated Effector Memory CD4+ T cells

14

4.5

2.1

0.5

4.1

3.0, 5.9

1.6, 8.3


Activated Effector Memory CD8+ T cells

14

9.4

5.2

1.4

7.8

7.0, 10.5

1.4, 24.2


Activated Naive CD4+ T cells

14

0.5

0.5

0.1

0.4

0.3, 0.6

0.1, 2.1


Activated Naive CD8+ T cells

14

1.7

1.3

0.3

1.3

0.9, 2.6

0.4, 4.7


Average CD4+ T cells

15

55.7

5.8

1.5

55.1

52.1, 58.0

42.5, 65.7


Average Lymphocytes

15

62.9

9.6

2.5

65.2

53.3, 71.3

45.6, 77.5


Average T cells

15

79.9

5.7

1.5

80.2

73.5, 84.7

71.4, 88.6


CD8+ T cells

14

20.7

6.9

1.8

20.8

13.7, 23.6

12.3, 37.9


Central Memory CD4+ T cells

14

49.1

11.0

2.9

47.9

43.7, 53.4

31.6, 77.6


Central Memory CD8+ T cells

14

12.7

5.2

1.4

11.5

10.0, 14.7

6.9, 26.4


Effector CD4+ T cells

14

5.0

4.4

1.2

4.4

0.7, 7.5

0.3, 13.0


Effector CD8+ T cells

14

38.2

10.8

2.9

37.0

31.0, 42.8

21.0, 56.0


Effector Memory CD4+ T cells

14

14.2

5.5

1.5

14.5

9.8, 15.9

6.6, 25.4


Effector Memory CD8+ T cells

14

13.2

7.4

2.0

12.6

8.4, 15.9

4.4, 33.6


Naive CD4+ T cells

14

31.4

13.2

3.5

31.1

22.5, 39.5

6.0, 59.0


Naive CD8+ T cells

14

35.9

11.7

3.1

32.5

29.2, 41.7

19.5, 67.7

Tfh

Activated T follicular helper

15

0.4

0.2

0.0

0.4

0.3, 0.6

0.1, 0.9


Medium Activated T follicular helper

15

17.1

3.5

0.9

17.0

14.5, 19.8

10.1, 23.2


T follicular helper

15

13.2

5.0

1.3

12.2

8.9, 16.4

6.9, 24.3


T follicular helper type 1

15

24.5

5.2

1.3

23.5

20.8, 26.9

16.7, 35.7


T follicular helper type 17

15

36.3

5.0

1.3

36.6

33.5, 38.7

27.2, 48.3


T follicular helper type 2

15

23.1

4.9

1.3

21.9

20.2, 26.2

14.9, 32.6


T follicular regulatory

15

3.8

1.2

0.3

3.7

3.0, 4.5

2.0, 6.7

Treg

Activated Memory Treg cells

15

44.8

8.6

2.2

46.3

36.2, 51.3

30.9, 59.6


Activated Naïve Treg cells

15

0.6

0.5

0.1

0.5

0.3, 1.1

0.1, 2.1


Effector Treg cells

15

78.9

8.0

2.1

78.4

73.6, 88.3

64.5, 91.6


HLA-DR- Memory Treg cells

15

48.7

7.6

2.0

47.3

42.5, 55.2

38.0, 62.3


HLA-DR- Naive Treg cells

15

5.8

2.5

0.6

6.3

3.4, 7.7

2.1, 9.3


Treg cells

15

6.5

2.3

0.6

6.3

4.3, 9.1

3.2, 9.7

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile