Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2g. Descriptive Summary for Female Subjects Aged 18-29 Years



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

16

11.5

5.6

1.4

9.9

7.6, 14.9

5.1, 22.9


IgD+ Memory B cells

16

7.7

4.5

1.1

7.0

5.1, 8.9

2.0, 18.3


IgD- Memory B cells

16

19.9

8.1

2.0

18.7

14.9, 23.2

10.9, 43.4


IgD-CD27- B cells

16

10.8

5.5

1.4

9.0

6.8, 13.5

3.7, 25.2


Naïve B cells

16

61.7

11.3

2.8

63.4

58.1, 69.0

31.6, 75.9


Plasma cells

16

1.3

0.7

0.2

1.2

0.7, 1.7

0.3, 2.3


Plasmablasts

16

0.5

0.3

0.1

0.4

0.3, 0.6

0.0, 1.3


Transitional B cells

16

4.6

2.9

0.7

4.2

2.1, 6.4

0.4, 9.8

DCMNK

CD11c+CD123+ DC (DC)

16

4.9

10.0

2.5

1.3

0.8, 3.1

0.2, 40.4


CD11c+CD123+ DC (Live Scatter)

16

0.1

0.2

0.0

0.0

0.0, 0.0

0.0, 0.7


CD14+ Monocytes

16

80.1

6.6

1.7

78.9

75.4, 85.8

63.7, 88.8


CD16+CD14- Monocytes

16

7.0

4.8

1.2

5.0

3.7, 11.8

0.5, 14.9


CD16+CD56+ NK cells

16

72.3

15.0

3.7

75.2

67.3, 83.5

25.4, 87.3


CD16+CD56- NK cells

16

9.5

7.8

1.9

6.8

4.7, 10.6

3.1, 31.9


CD16-CD56+ NK cells

16

17.4

14.2

3.6

13.6

8.9, 19.7

5.5, 65.7


Classical Monocytes

16

78.3

7.0

1.7

77.2

74.1, 84.0

61.4, 87.5


Dendritic cells (Lin-)

16

1.6

0.7

0.2

1.6

1.3, 1.9

0.4, 3.1


Dendritic cells (Live Scatter)

16

1.2

0.4

0.1

1.2

1.0, 1.6

0.3, 2.0


Monocytes

16

10.0

5.0

1.3

9.2

7.0, 14.0

2.4, 19.1


Myeloid DC (DC)

16

44.9

10.1

2.5

46.0

35.3, 51.1

28.9, 62.6


Myeloid DC (Live Scatter)

16

0.6

0.2

0.1

0.6

0.4, 0.7

0.1, 0.9


NK cells

16

7.2

4.4

1.1

5.3

4.2, 9.3

3.2, 19.3


Plasmacytoid DC (DC)

16

29.6

8.0

2.0

31.2

25.6, 35.4

15.0, 41.0


Plasmacytoid DC (Live Scatter)

16

0.4

0.2

0.0

0.3

0.3, 0.4

0.1, 0.7

Tcell

Activated CD4+ T cells

16

1.7

0.6

0.2

1.5

1.2, 2.3

0.9, 2.8


Activated CD8+ T cells

16

5.4

3.7

0.9

4.9

2.8, 6.3

1.9, 16.6


Activated Central Memory CD4+ T cells

16

1.8

0.6

0.2

1.8

1.2, 2.3

1.0, 2.9


Activated Central Memory CD8+ T cells

16

9.5

5.2

1.3

8.5

5.9, 11.7

3.2, 21.4


Activated Effector CD4+ T cells

16

3.3

2.1

0.5

2.9

1.6, 5.1

0.3, 7.1


Activated Effector CD8+ T cells

16

8.8

8.3

2.1

7.0

3.3, 11.4

1.8, 35.5


Activated Effector Memory CD4+ T cells

16

6.3

2.6

0.7

5.9

4.2, 8.3

2.8, 11.2


Activated Effector Memory CD8+ T cells

16

17.9

12.4

3.1

14.1

10.4, 21.6

6.1, 54.8


Activated Naive CD4+ T cells

16

0.9

0.6

0.2

0.7

0.4, 1.1

0.2, 2.5


Activated Naive CD8+ T cells

16

2.2

1.6

0.4

1.8

0.8, 3.2

0.6, 5.4


Average CD4+ T cells

16

47.3

6.1

1.5

48.4

44.5, 50.8

32.6, 56.1


Average Lymphocytes

16

69.6

7.1

1.8

70.0

66.7, 74.7

53.9, 80.6


Average T cells

16

76.6

6.1

1.5

74.5

72.6, 82.7

66.7, 85.4


CD8+ T cells

16

22.3

5.9

1.5

20.7

19.0, 26.0

12.5, 33.7


Central Memory CD4+ T cells

16

37.2

9.3

2.3

37.8

29.4, 43.0

23.2, 59.0


Central Memory CD8+ T cells

16

6.0

2.9

0.7

6.1

3.1, 7.8

2.3, 11.7


Effector CD4+ T cells

16

1.4

1.4

0.3

1.0

0.7, 1.3

0.2, 5.2


Effector CD8+ T cells

16

25.7

11.2

2.8

23.9

16.9, 29.7

11.5, 51.6


Effector Memory CD4+ T cells

16

8.6

2.9

0.7

8.6

7.0, 9.4

2.9, 15.1


Effector Memory CD8+ T cells

16

8.2

4.5

1.1

8.8

4.0, 10.6

2.4, 18.3


Naive CD4+ T cells

16

52.6

9.7

2.4

51.0

45.3, 63.0

34.9, 66.6


Naive CD8+ T cells

16

60.0

9.9

2.5

62.3

52.1, 66.6

42.6, 78.1

Tfh

Activated T follicular helper

16

0.6

0.3

0.1

0.5

0.4, 0.7

0.3, 1.2


Medium Activated T follicular helper

16

20.3

4.2

1.0

20.6

16.4, 23.3

12.9, 27.8


T follicular helper

16

11.4

2.8

0.7

12.0

8.8, 13.7

6.9, 14.9


T follicular helper type 1

16

29.8

6.5

1.6

30.7

24.9, 35.3

16.9, 39.0


T follicular helper type 17

16

29.5

6.7

1.7

28.2

23.9, 34.6

18.3, 40.6


T follicular helper type 2

16

26.7

5.8

1.5

25.7

23.6, 30.4

17.8, 40.0


T follicular regulatory

16

3.8

1.2

0.3

3.6

2.9, 4.5

1.2, 5.9

Treg

Activated Memory Treg cells

16

44.0

7.2

1.8

43.8

38.5, 50.1

31.1, 54.2


Activated Naïve Treg cells

16

1.9

1.3

0.3

1.6

1.1, 2.6

0.4, 5.6


Effector Treg cells

16

53.4

12.7

3.2

53.4

45.2, 61.7

34.3, 78.8


HLA-DR- Memory Treg cells

16

43.8

7.9

2.0

42.5

39.4, 51.7

29.1, 56.0


HLA-DR- Naive Treg cells

16

10.2

3.8

1.0

10.3

7.9, 12.4

4.7, 17.5


Treg cells

16

6.6

1.4

0.4

6.5

5.8, 7.4

3.5, 9.2

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile