Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2f. Descriptive Summary for Female Subjects



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

62

11.4

5.3

0.7

10.2

7.8, 13.5

1.8, 29.1


IgD+ Memory B cells

62

7.9

5.0

0.6

7.0

4.6, 10.0

1.3, 28.0


IgD- Memory B cells

62

19.9

8.5

1.1

19.2

13.5, 25.4

5.2, 43.4


IgD-CD27- B cells

62

8.7

5.1

0.6

6.9

4.8, 11.7

2.2, 25.2


Naïve B cells

62

63.5

12.5

1.6

66.5

57.4, 70.7

26.8, 86.6


Plasma cells

62

1.0

0.8

0.1

0.7

0.5, 1.3

0.1, 3.7


Plasmablasts

62

0.4

0.4

0.0

0.3

0.2, 0.4

0.0, 1.6


Transitional B cells

62

5.1

3.8

0.5

4.1

2.6, 6.3

0.4, 21.1

DCMNK

CD11c+CD123+ DC (DC)

62

6.9

8.3

1.1

2.7

1.1, 10.3

0.1, 40.4


CD11c+CD123+ DC (Live Scatter)

62

0.1

0.1

0.0

0.0

0.0, 0.1

0.0, 0.7


CD14+ Monocytes

62

79.7

7.4

0.9

79.9

76.2, 84.9

54.3, 93.1


CD16+CD14- Monocytes

62

9.2

5.2

0.7

8.5

4.9, 13.4

0.5, 22.5


CD16+CD56+ NK cells

62

76.8

11.5

1.5

78.4

71.0, 85.9

25.4, 91.1


CD16+CD56- NK cells

62

9.9

7.3

0.9

7.8

5.0, 11.9

2.5, 35.0


CD16-CD56+ NK cells

62

12.5

8.9

1.1

10.5

6.8, 15.6

3.7, 65.7


Classical Monocytes

62

77.2

7.8

1.0

77.3

73.3, 83.0

51.3, 92.3


Dendritic cells (Lin-)

62

1.6

0.7

0.1

1.5

1.2, 2.0

0.4, 4.7


Dendritic cells (Live Scatter)

62

1.2

0.5

0.1

1.1

0.8, 1.5

0.3, 2.7


Monocytes

62

10.9

3.8

0.5

10.2

8.2, 14.2

2.4, 19.1


Myeloid DC (DC)

62

44.9

11.8

1.5

44.9

35.0, 52.2

18.8, 72.7


Myeloid DC (Live Scatter)

62

0.5

0.3

0.0

0.5

0.3, 0.7

0.1, 1.4


NK cells

62

9.0

5.3

0.7

7.3

4.9, 12.1

2.4, 24.3


Plasmacytoid DC (DC)

62

26.1

10.2

1.3

25.0

17.5, 33.1

9.9, 55.0


Plasmacytoid DC (Live Scatter)

62

0.3

0.1

0.0

0.3

0.2, 0.4

0.1, 0.7

Tcell

Activated CD4+ T cells

59

1.7

0.9

0.1

1.5

1.2, 2.2

0.4, 5.8


Activated CD8+ T cells

59

5.4

3.8

0.5

4.3

2.6, 7.2

0.9, 19.0


Activated Central Memory CD4+ T cells

59

1.6

0.7

0.1

1.4

1.0, 2.2

0.4, 3.7


Activated Central Memory CD8+ T cells

58

5.9

4.1

0.5

4.5

3.2, 7.8

1.2, 21.4


Activated Effector CD4+ T cells

59

3.8

2.7

0.4

3.2

1.6, 5.7

0.3, 10.3


Activated Effector CD8+ T cells

58

9.0

7.8

1.0

7.3

3.3, 11.6

1.4, 38.4


Activated Effector Memory CD4+ T cells

59

5.9

3.2

0.4

5.4

3.7, 7.1

1.5, 21.8


Activated Effector Memory CD8+ T cells

58

13.7

9.5

1.2

10.7

7.6, 18.0

1.4, 54.8


Activated Naive CD4+ T cells

59

0.9

0.7

0.1

0.7

0.3, 1.5

0.1, 3.1


Activated Naive CD8+ T cells

58

1.9

1.5

0.2

1.4

0.7, 2.8

0.3, 5.5


Average CD4+ T cells

62

52.3

7.8

1.0

52.2

47.0, 57.8

32.6, 66.9


Average Lymphocytes

62

65.8

8.0

1.0

67.4

61.7, 71.1

45.6, 80.6


Average T cells

62

78.1

6.7

0.9

78.3

73.0, 83.1

64.1, 93.0


CD8+ T cells

59

21.3

5.6

0.7

21.0

17.3, 23.9

11.5, 37.9


Central Memory CD4+ T cells

59

44.6

10.9

1.4

45.1

37.8, 51.2

22.3, 77.6


Central Memory CD8+ T cells

58

9.9

5.2

0.7

9.0

6.2, 12.7

2.3, 26.4


Effector CD4+ T cells

59

2.6

3.2

0.4

1.1

0.6, 3.5

0.1, 13.0


Effector CD8+ T cells

58

28.7

13.1

1.7

26.4

18.0, 37.1

7.2, 61.3


Effector Memory CD4+ T cells

59

10.8

5.2

0.7

9.3

7.2, 12.8

2.9, 28.4


Effector Memory CD8+ T cells

58

10.8

6.2

0.8

9.8

6.4, 15.3

2.3, 33.6


Naive CD4+ T cells

59

41.7

13.6

1.8

42.8

32.8, 52.1

6.0, 66.6


Naive CD8+ T cells

58

50.6

15.3

2.0

50.8

36.1, 62.9

19.5, 79.5

Tfh

Activated T follicular helper

62

0.5

0.2

0.0

0.4

0.3, 0.6

0.1, 1.2


Medium Activated T follicular helper

62

17.8

4.3

0.5

16.9

15.0, 20.9

8.8, 27.8


T follicular helper

62

12.5

3.8

0.5

12.4

9.5, 14.5

6.9, 24.3


T follicular helper type 1

62

27.8

6.1

0.8

27.1

23.3, 32.5

16.7, 42.1


T follicular helper type 17

62

32.3

6.4

0.8

33.4

27.7, 36.8

18.3, 48.3


T follicular helper type 2

62

23.9

5.3

0.7

23.6

20.2, 27.4

14.8, 40.0


T follicular regulatory

62

4.6

2.0

0.3

4.4

3.2, 5.4

1.2, 12.2

Treg

Activated Memory Treg cells

62

45.8

8.0

1.0

47.1

40.1, 50.9

24.7, 63.4


Activated Naïve Treg cells

62

1.4

1.4

0.2

0.9

0.5, 1.7

0.1, 7.6


Effector Treg cells

62

65.5

13.6

1.7

64.7

57.5, 74.9

34.3, 91.6


HLA-DR- Memory Treg cells

62

45.4

8.4

1.1

45.3

40.0, 51.6

24.6, 67.0


HLA-DR- Naive Treg cells

62

7.5

3.6

0.5

7.3

5.0, 8.6

2.1, 20.5


Treg cells

62

6.8

1.7

0.2

6.8

5.6, 7.9

3.2, 10.6

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile