Study to Define Adult Normative Ranges for Polychromatic Flow Cytometry Assays (Grifols)


Table 2r. Descriptive Summary for Female, Caucasian Subjects



Panel

Cell Subset

N

Mean

SD

SE

Median

Q1, Q3

Min, Max

Bcell

B cells

27

9.2

3.5

0.7

9.8

6.0, 11.4

1.8, 15.3


IgD+ Memory B cells

27

10.1

4.4

0.8

9.3

6.7, 13.0

4.1, 18.3


IgD- Memory B cells

27

20.1

9.7

1.9

17.1

11.8, 25.4

5.2, 43.4


IgD-CD27- B cells

27

8.1

4.7

0.9

6.7

4.0, 12.0

2.2, 17.5


Naïve B cells

27

61.7

13.7

2.6

64.9

54.8, 71.1

26.8, 84.3


Plasma cells

27

0.8

0.5

0.1

0.7

0.5, 1.0

0.1, 2.3


Plasmablasts

27

0.3

0.2

0.0

0.3

0.2, 0.4

0.1, 1.3


Transitional B cells

27

4.6

2.9

0.6

3.9

2.7, 6.3

0.4, 11.7

DCMNK

CD11c+CD123+ DC (DC)

27

5.5

6.4

1.2

2.7

0.9, 8.9

0.1, 22.1


CD11c+CD123+ DC (Live Scatter)

27

0.1

0.1

0.0

0.0

0.0, 0.1

0.0, 0.4


CD14+ Monocytes

27

82.5

5.2

1.0

82.1

78.2, 87.1

75.0, 93.1


CD16+CD14- Monocytes

27

6.5

3.7

0.7

5.2

4.3, 9.8

1.7, 15.3


CD16+CD56+ NK cells

27

76.8

9.8

1.9

76.7

69.2, 87.3

53.0, 89.8


CD16+CD56- NK cells

27

8.8

7.0

1.4

6.9

4.2, 9.1

2.6, 31.9


CD16-CD56+ NK cells

27

13.6

6.9

1.3

13.9

7.1, 19.6

4.8, 27.9


Classical Monocytes

27

80.8

5.7

1.1

80.5

76.2, 85.6

71.9, 92.3


Dendritic cells (Lin-)

27

1.5

0.6

0.1

1.3

1.2, 1.8

0.6, 3.1


Dendritic cells (Live Scatter)

27

1.1

0.4

0.1

1.0

0.8, 1.4

0.4, 2.2


Monocytes

27

10.9

3.6

0.7

10.1

8.2, 14.2

6.1, 19.1


Myeloid DC (DC)

27

47.3

11.7

2.2

47.4

40.7, 53.2

20.7, 72.7


Myeloid DC (Live Scatter)

27

0.6

0.3

0.1

0.5

0.3, 0.7

0.1, 1.4


NK cells

27

8.5

5.5

1.0

6.9

4.0, 11.6

2.4, 24.3


Plasmacytoid DC (DC)

27

27.6

10.8

2.1

26.1

18.8, 37.6

12.5, 51.4


Plasmacytoid DC (Live Scatter)

27

0.3

0.2

0.0

0.3

0.2, 0.4

0.1, 0.7

Tcell

Activated CD4+ T cells

27

1.7

0.6

0.1

1.6

1.2, 2.0

0.6, 2.9


Activated CD8+ T cells

27

6.1

3.9

0.7

5.3

2.7, 8.1

1.1, 16.6


Activated Central Memory CD4+ T cells

27

1.7

0.7

0.1

1.5

1.1, 2.3

0.7, 2.9


Activated Central Memory CD8+ T cells

26

6.8

5.0

1.0

5.1

3.8, 8.2

1.7, 21.4


Activated Effector CD4+ T cells

27

4.1

2.6

0.5

3.7

1.6, 5.9

0.5, 10.3


Activated Effector CD8+ T cells

26

11.2

9.3

1.8

9.3

3.8, 12.8

1.4, 38.4


Activated Effector Memory CD4+ T cells

27

5.9

2.5

0.5

6.1

3.8, 8.0

1.6, 10.7


Activated Effector Memory CD8+ T cells

26

14.8

11.9

2.3

10.5

6.4, 22.6

3.1, 54.8


Activated Naive CD4+ T cells

27

0.9

0.6

0.1

0.8

0.4, 1.2

0.1, 2.3


Activated Naive CD8+ T cells

26

1.9

1.2

0.2

1.4

1.1, 2.9

0.4, 4.7


Average CD4+ T cells

27

54.1

7.2

1.4

53.7

49.4, 59.1

39.6, 66.3


Average Lymphocytes

27

64.7

8.0

1.5

66.3

59.2, 70.9

47.8, 77.4


Average T cells

27

79.6

7.3

1.4

80.3

74.4, 85.3

64.1, 93.0


CD8+ T cells

27

21.1

5.3

1.0

20.9

18.7, 22.5

11.5, 32.9


Central Memory CD4+ T cells

27

44.8

10.7

2.1

43.1

37.5, 53.3

26.8, 67.8


Central Memory CD8+ T cells

26

12.2

5.7

1.1

10.6

7.3, 14.8

4.1, 26.4


Effector CD4+ T cells

27

2.2

3.0

0.6

1.0

0.5, 3.3

0.1, 11.8


Effector CD8+ T cells

26

25.5

11.3

2.2

23.8

17.4, 34.4

8.5, 56.0


Effector Memory CD4+ T cells

27

9.7

5.3

1.0

8.5

6.3, 11.0

2.9, 28.4


Effector Memory CD8+ T cells

26

12.7

5.0

1.0

11.4

9.3, 15.8

5.9, 24.2


Naive CD4+ T cells

27

43.1

12.9

2.5

46.0

32.8, 52.9

23.4, 65.0


Naive CD8+ T cells

26

49.5

13.5

2.6

49.1

37.2, 61.1

25.5, 71.1

Tfh

Activated T follicular helper

27

0.5

0.3

0.0

0.4

0.3, 0.6

0.1, 1.2


Medium Activated T follicular helper

27

17.6

4.4

0.8

16.6

14.4, 22.5

8.8, 24.8


T follicular helper

27

11.5

2.9

0.6

11.2

8.5, 13.9

6.9, 16.7


T follicular helper type 1

27

32.3

5.1

1.0

32.9

28.3, 36.0

22.7, 42.1


T follicular helper type 17

27

28.3

5.5

1.1

27.7

23.8, 33.5

18.3, 38.7


T follicular helper type 2

27

24.6

5.4

1.0

23.8

20.7, 27.7

17.9, 40.0


T follicular regulatory

27

4.8

2.3

0.4

4.4

3.0, 5.4

2.2, 12.2

Treg

Activated Memory Treg cells

27

47.9

6.0

1.2

49.0

42.8, 50.9

31.1, 61.1


Activated Naïve Treg cells

27

1.3

0.9

0.2

1.1

0.7, 2.1

0.2, 3.1


Effector Treg cells

27

61.7

13.5

2.6

62.6

50.2, 66.8

39.9, 88.3


HLA-DR- Memory Treg cells

27

43.9

6.5

1.2

44.1

39.7, 47.5

32.3, 58.2


HLA-DR- Naive Treg cells

27

6.8

2.4

0.5

6.3

4.9, 8.5

2.8, 13.2


Treg cells

27

6.1

1.8

0.3

6.1

4.9, 7.0

3.2, 10.6

Summary Statistics


Two DCMNK gates are not reported because their values are ANR.


N: number of observations; SD: standard deviation; SE: standard error; Q1: 25th percentile; Q3: 75th percentile